Expert Interview: Dr. Christian Guilleminault on UARS

This month, I interview Dr. Christian Guilleminault of Stanford University, who is one of the pioneers in sleep apnea diagnosis and treatment. We’re going to focus on Upper Airway Resistance Syndrome (UARS), which he discovered.

Here are some of the questions we covered:

– Describe to us what UARS is and how it’s different from OSA?

– Why is the AHI is limited when it comes to picking up UARS?

– How to diagnose UARS: Esophageal manometry vs. nasal cannula.

– How UARS patients have intact nervous systems, whereas sleep apnea (OSA) patients have diminished nervous systems, and what may cause progression from UARS to OSA?

– How do you treat patients with UARS? How is it different from treating sleep apnea?

– What are the dental options for UARS?

– How common is UARS in children and how can they be treated?

And much more…

Download MP3

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10 thoughts on “Expert Interview: Dr. Christian Guilleminault on UARS

  1. I don’t have a specific quequeBstion, just interested in the subject. I am tired of being tired. I have had a sleep study 10 years ago and last year did the overnight thing where you wear the gadget that monitors your breathing while you sleep. I don’t remember the specific results but it apparently didn’t show that I needed to have another sleep study.

    I will have to listen to the recorded event and look forward to it.


    Steve McLemore

  2. Dear Dr. Park,

    Your article by Dr. Christian Guilleminault on UARS is very interesting,
    the problem is, having such information is not enough, as, in many countries
    access to sleep doctors who are receptive to new information is rare.

    For example, in the UK, most sleep disorders go completely untreated
    or perhaps go treated using the wrong medication, which often make the conditions worse, such as SSRI’s.

    What path of action would you recommend for someone like myself, living in an back ward or low funded area (UK) who believes they have such a sleep disorder and wants to be tested and ideally get treatment for the illness.

    Do you know of clinics that recognize the doctors work and who treat the condition?

    Please help. Please contact me via email given above.

  3. Sorry to trouble you guys,
    but how about Dr. Christian Guilleminault writing a book
    or sending his articles to all the official national governing bodies of Sleep Medicine and Psychiatry so that his research is embraced by at least those who are receptive.
    Otherwise, people are held to ransom by their own local sleep doctors, who often lack up to date information and in some cases, are completely useless.

    Please write more books and help.

  4. Dr. Park’s work was recommended to me by allergist and orofunctional myologist, but I am well acquainted with Dr. Park’s Sleep Interrupted which introduced me to UARS, mouth breathing. I would like to see interview with UARS pioneer, Dr. Guillemineault.
    Have formerly led a sleep apnea support group in the San Francisco Bay Area.

  5. An outstanding share! I have just forwarded this onto a
    friend who has been doing a little homework on this. And he in fact
    bought me breakfast because I discovered it for him…
    lol. So let me reword this…. Thank YOU for the
    meal!! But yeah, thanks for spending time to discuss this topic here on your internet site.

  6. I am a 57 year old female. I just had a sleep study. My number was 68 times in 1 hour. I was on a bipap machine over 12 years ago but could not adjust to wearing a mask. The mask have improved now and I am going to give it another try. I open mouth breathe alot as well. I have the acid reflux as well. After the study and being put on a CPAP machine, I felt better. And I was only on it for about 4 hours. I also have type 2 diabetes and have gained 50 pounds over the last 2 years. Even though I am going back on the CPAP, he wants me to see a specialist still. I also lost my voice 3 months ago and doing voice therapy. My therapist said that he felt like this was caused by the muscles in my throat are weakened. I am going to address this UARS with the specialist when I see her. I find it very interesting.